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81.
Kolmachikhina E. B. Sviridov A.V. Naumov K. D. 《Russian Journal of Non-Ferrous Metals》2020,61(5):488-493
Russian Journal of Non-Ferrous Metals - This article is devoted to the influence of sodium lignosulfonate (SL), anionic surfactants (sodium dodecylsulfate (SDS), sodium dodecylbenzene sulfonate... 相似文献
82.
Akopdzhanyan T. G. Chemagina E. A. Borovinskaya I. P. 《Russian Journal of Non-Ferrous Metals》2020,61(6):686-690
Russian Journal of Non-Ferrous Metals - The synthesis and sintering of the (AlN)x(SiC)1 – x solid solution have been studied under conditions of self-propagating high-temperature synthesis... 相似文献
83.
Madhu H. C. Edachery Vimal Lijesh K. P. Perugu Chandra Shekhar Kailas Satish V. 《Metallurgical and Materials Transactions A》2020,51(8):4086-4099
Metallurgical and Materials Transactions A - Hybrid nanocomposites have potential as wear-resistant materials. However, synthesizing these nanocomposites by conventional molten state methods result... 相似文献
84.
E. M. Godzhaev R. A. Bairamov R. A. Abbasov 《Surface Engineering and Applied Electrochemistry》2015,51(6):552-556
The paper describes the results of a study on the temperature and frequency dependences of the dielectric permeability and dielectric loss tangent of composite materials composed of low density polyethylene filled with cadmium sulfide (LDPE/CdS) and indium(III) selenide (LDPE/In2Se3) in the temperature range of 300–450 K and a frequency range of 0–1014 Hz. It is revealed that a variation in the filler content and the effect of external factors can yield novel composite materials with desired dielectric characteristics. 相似文献
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Dr. Jiayao Y. Wang Dr. Jiaqi Q. Li Prof. Dr. Yumei M. Xiao Prof. Dr. Bin Fu Prof. Dr. Zhaohai H. Qin 《ChemMedChem》2020,15(5):404-410
Mitochondrial oxidative damage and dysfunction contribute to a wide range of human diseases. Considering the limitation of conventional antioxidants and that mitochondria are the main source of reactive oxygen species (ROS) which induce oxidative damage, mitochondria-targeted antioxidants which can selectively block mitochondrial oxidative damage and prevent various types of cell death have been widely developed. As a lipophilic cation, triphenylphosphonium (TPP) has been commonly used in designing mitochondria-targeted antioxidants. Conjugated with the TPP moiety, antioxidants can achieve more than 1000-fold higher mitochondrial concentration depending on cell membrane potentials and mitochondrial membrane potentials. Herein we discuss the deficiencies of conventional antioxidants and the advantages of mitochondrial targeting, and review various types of TPP-based mitochondria-targeted antioxidants. These provide theoretical and background support for the design of new anti-oxidant. 相似文献
89.
Potential mGAT4 inhibitors derived from the lead substance (S)-SNAP-5114 have been synthesized and characterized for their inhibitory potency. Variations from the parent compound included the substitution of one of its aromatic 4-methoxy and 4-methoxyphenyl groups, respectively, with a more polar moiety, including a carboxylic acid, alcohol, nitrile, carboxamide, sulfonamide, aldehyde or ketone function, or amino acid partial structures. Furthermore, it was investigated how the substitution of more than one of the aromatic 4-methoxy groups affects the potency and selectivity of the resulting compounds. Among the synthesized test substances (S)-1-{2-[(4-formylphenyl)bis(4-methoxyphenyl)-methoxy]ethyl}piperidine-3-carboxylic acid, that features a carbaldehyde function in place of one of the aromatic 4-methoxy moieties of (S)-SNAP-5114, was found to have a pIC50 value of 5.89±0.07, hence constituting a slightly more potent mGAT4 inhibitor than the parent substance while showing comparable subtype selectivity. 相似文献
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